Calming Wipes is a natural way of supporting anxiety and stress in pets such as cats and dogs. Pet Remedy works alongside the brains natural messengers called neuro-transmitters, which work by telling the nerve receiving the message to either calm down or get fired up. In times of stress or anxiety the nerves get over stimulated, which leads on to the many symptoms we see in our pets. The special Pet Remedy blend of essentials oils (low dosage valerian essential oil with vetiver, sweet basil and sage) works alongside these natural relaxation pathways to help calm the nerves of anxious or stressed pets. Works immediately.